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Control of S phase duration: a replication capacity model with E2F transcription at its heart

DNA replication capacity, the maximal amount of DNA a cell can synthesize at any given time during S phase, is controlled by E2F-dependent transcription. Controlling replication capacity limits the replication rate and provides a robust mechanism to keep replication fork speed within an optimal rang...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Bertoli, Cosetta, de Bruin, Robertus A.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018357/
https://ncbi.nlm.nih.gov/pubmed/33855165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1839294
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