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Sustained E2F-Dependent Transcription Is a Key Mechanism to Prevent Replication-Stress-Induced DNA Damage

Recent work established DNA replication stress as a crucial driver of genomic instability and a key event at the onset of cancer. Post-translational modifications play an important role in the cellular response to replication stress by regulating the activity of key components to prevent replication...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Bertoli, Cosetta, Herlihy, Anna E., Pennycook, Betheney R., Kriston-Vizi, Janos, de Bruin, Robertus A.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893157/
https://ncbi.nlm.nih.gov/pubmed/27160911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.036
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