Conessine Interferes with Oxidative Stress-Induced C2C12 Myoblast Cell Death through Inhibition of Autophagic Flux

Conessine, a steroidal alkaloid isolated from Holarrhena floribunda, has anti-malarial activity and interacts with the histamine H3 receptor. However, the cellular effects of conessine are poorly understood. Accordingly, we evaluated the involvement of conessine in the regulation of autophagy. We se...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kim, Hyunju, Lee, Kang Il, Jang, Minsu, Namkoong, Sim, Park, Rackhyun, Ju, Hyunwoo, Choi, Inho, Oh, Won Keun, Park, Junsoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892631/
https://ncbi.nlm.nih.gov/pubmed/27257813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157096
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