Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells

Crosslinking of regulatory immunoreceptors (RR), such as BDCA-2 (CD303) or ILT7 (CD85g), of plasmacytoid dendritic cells (pDCs) efficiently suppresses production of type-I interferon (IFN)-α/β and other cytokines in response to Toll-like receptor (TLR) 7/9 ligands. This cytokine-inhibitory pathway i...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Aouar, Besma, Kovarova, Denisa, Letard, Sebastien, Font-Haro, Albert, Florentin, Jonathan, Weber, Jan, Durantel, David, Chaperot, Laurence, Plumas, Joel, Trejbalova, Katerina, Hejnar, Jiri, Nunès, Jacques A., Olive, Daniel, Dubreuil, Patrice, Hirsch, Ivan, Stranska, Ruzena
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892542/
https://ncbi.nlm.nih.gov/pubmed/27258042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156063
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