Φορτώνει......
CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development
The SLAM family receptors contribute to diverse aspects of lymphocyte biology and signal via the small adaptor molecule SAP. Mutations affecting SAP lead to X-linked lymphoproliferative syndrome Type 1, a severe immunodysregulation characterized by fulminant mononucleosis, dysgammaglobulinemia, and...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | PLoS One |
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Κύριοι συγγραφείς: | , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Public Library of Science
2016
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892526/ https://ncbi.nlm.nih.gov/pubmed/27258160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156072 |
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