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As time goes by: Evolutive interplay between endogenous retrolements and the KRAB’n’KAP system

Close to 50% of the human genome is derived from endogenous retroelements, which are both formidable evolutionary forces and threats to its integrity. Accordingly, these genetic invaders are subjected to transcriptional repression from the very first days of embryogenesis. Reporting in Nature, Jacob...

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Publicat a:Dev Cell
Autors principals: Imbeault, Michael, Trono, Didier
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892340/
https://ncbi.nlm.nih.gov/pubmed/25453824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.10.019
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