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As time goes by: Evolutive interplay between endogenous retrolements and the KRAB’n’KAP system

Close to 50% of the human genome is derived from endogenous retroelements, which are both formidable evolutionary forces and threats to its integrity. Accordingly, these genetic invaders are subjected to transcriptional repression from the very first days of embryogenesis. Reporting in Nature, Jacob...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Dev Cell
Hauptverfasser: Imbeault, Michael, Trono, Didier
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892340/
https://ncbi.nlm.nih.gov/pubmed/25453824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.10.019
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