Compromised fidelity of B‐cell tolerance checkpoints in AChR and MuSK myasthenia gravis

OBJECTIVE: Myasthenia gravis (MG) is an autoimmune condition in which neurotransmission is impaired by binding of autoantibodies to acetylcholine receptors (AChR) or, in a minority of patients, to muscle specific kinase (MuSK). There are differences in the dominant IgG subclass, pathogenic mechanism...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Lee, Jae‐Yun, Stathopoulos, Panos, Gupta, Sasha, Bannock, Jason M., Barohn, Richard J., Cotzomi, Elizabeth, Dimachkie, Mazen M., Jacobson, Leslie, Lee, Casey S., Morbach, Henner, Querol, Luis, Shan, Jing‐Li, Vander Heiden, Jason A., Waters, Patrick, Vincent, Angela, Nowak, Richard J., O'Connor, Kevin C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891998/
https://ncbi.nlm.nih.gov/pubmed/27547772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.311
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