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mTOR signaling: new networks for ALL

Compared with rapamycin, mammalian target of rapamycin (mTOR) dual inhibitors have shown improved ability to kill acute lymphocytic leukemia (ALL) cells in preclinical models. In this issue of Blood, Yun et al have identified novel signaling pathways downstream of mTOR that are disrupted by dual inh...

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Detalles Bibliográficos
Publicado en:Blood
Autor Principal: Fruman, David A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891950/
https://ncbi.nlm.nih.gov/pubmed/27257176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-703199
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