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T cells expressing CD19-specific Engager Molecules for the Immunotherapy of CD19-positive Malignancies
T cells expressing chimeric antigen receptors (CARs) or the infusion of bispecific T-cell engagers (BITEs) have shown antitumor activity in humans for CD19-positive malignancies. While BITEs redirect the large reservoir of resident T cells to tumors, CAR T cells rely on significant in vivo expansion...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891739/ https://ncbi.nlm.nih.gov/pubmed/27255991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27130 |
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