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Engager T Cells: A New Class of Antigen-specific T Cells That Redirect Bystander T Cells

Adoptive immunotherapy with antigen-specific T cells has shown promise for the treatment of malignancies. However, infused T cells are unable to redirect resident T cells, limiting potential benefit. While the infusion of bispecific T-cell engagers can redirect resident T cells to tumors, these mole...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mol Ther
Hauptverfasser: Iwahori, Kota, Kakarla, Sunitha, Velasquez, Mireya P, Yu, Feng, Yi, Zongzhen, Gerken, Claudia, Song, Xiao-Tong, Gottschalk, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426792/
https://ncbi.nlm.nih.gov/pubmed/25142939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.156
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