The sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and c-Met

The sonic hedgehog (Shh) pathway is highly activated in thyroid neoplasms and promotes thyroid cancer stem-like cell phenotype, but whether the Shh pathway regulates thyroid tumor cell motility and invasiveness remains unknown. Here, we report that the motility and invasiveness of two anaplastic thy...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Williamson, Ashley J., Doscas, Michelle E., Ye, Jin, Heiden, Katherine B., Xing, Mingzhao, Li, Yi, Prinz, Richard A., Xu, Xiulong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891133/
https://ncbi.nlm.nih.gov/pubmed/26859575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7228
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