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Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway
Statins (3-hydroxy-3-methylglutaryl coenzyme A [HMG-CoA] reductase inhibitors) are well-established agents to treat hyperlipidemic states. Experimental and epidemiological evidence further implies an anticancer effect of these substances. This study investigates the mechanism underlying human lung c...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891124/ https://ncbi.nlm.nih.gov/pubmed/26863638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7213 |
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