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Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib
The antitumorigenic mechanism of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib is still a matter of debate. Among different structurally related COX-2 inhibitors, only celecoxib was found to cause apoptosis and cell death of human lung cancer cells (IC(50) values of 19.96 µM [A549], 12....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3793616/ https://ncbi.nlm.nih.gov/pubmed/23943857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M042283 |
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