The transcription factor GATA1 and the histone methyltransferase SET7 interact to promote VEGF-mediated angiogenesis and tumor growth and predict clinical outcome of breast cancer

Angiogenesis is essential for tumor growth. Vascular endothelial growth factor (VEGF) is the most important regulator of tumor angiogenesis. However, how transcription factors interact with histone-modifying enzymes to regulate VEGF transcription and tumor angiogenesis remains unclear. Here, we show...

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Pubblicato in:Oncotarget
Autori principali: Zhang, Yanan, Liu, Jie, Lin, Jing, Zhou, Lei, Song, Yuhua, Wei, Bo, Luo, Xiaoli, Chen, Zhida, Chen, Yingjie, Xiong, Jiaxiu, Xu, Xiaojie, Ding, Lihua, Ye, Qinong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891089/
https://ncbi.nlm.nih.gov/pubmed/26848522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7126
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