The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners

The DEK oncogene is overexpressed in various cancers and overexpression of DEK correlates with poor clinical outcome. Vascular endothelial growth factor (VEGF) is the most important regulator of tumor angiogenesis, a process essential for tumor growth and metastasis. However, whether DEK enhances tu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Yanan, Liu, Jie, Wang, Shibin, Luo, Xiaoli, Li, Yang, Lv, Zhaohui, Zhu, Jie, Lin, Jing, Ding, Lihua, Ye, Qinong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029660/
https://ncbi.nlm.nih.gov/pubmed/26988756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8060
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