The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners

The DEK oncogene is overexpressed in various cancers and overexpression of DEK correlates with poor clinical outcome. Vascular endothelial growth factor (VEGF) is the most important regulator of tumor angiogenesis, a process essential for tumor growth and metastasis. However, whether DEK enhances tu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Zhang, Yanan, Liu, Jie, Wang, Shibin, Luo, Xiaoli, Li, Yang, Lv, Zhaohui, Zhu, Jie, Lin, Jing, Ding, Lihua, Ye, Qinong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029660/
https://ncbi.nlm.nih.gov/pubmed/26988756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8060
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