Polycomb complex protein BMI-1 promotes invasion and metastasis of pancreatic cancer stem cells by activating PI3K/AKT signaling, an ex vivo, in vitro, and in vivo study

Cancer stem cell theory indicates cancer stem cells are the key to promote tumor invasion and metastasis. Studies showed that BMI-1 could promote self-renew, differentiation and tumor formation of CSCs and invasion/metastasis of human cancer. However, whether BMI-1 could regulate invasion and metast...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Min-Cong, Jiao, Min, Wu, Tao, Jing, Li, Cui, Jie, Guo, Hui, Tian, Tao, Ruan, Zhi-ping, Wei, Yong-Chang, Jiang, Li-Li, Sun, Hai-Feng, Huang, Lan-Xuan, Nan, Ke-Jun, Li, Chun-Li
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891062/
https://ncbi.nlm.nih.gov/pubmed/26840020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7078
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