The expressions of Hedgehog and PI3K-AKT pathway components correlate with invasion and metastasis in hepatocellular carcinoma

Objective: To investigate the expression and clinical significance of Shh, Gli1, FAK, p-FAK and p-AKT in HCC. Methods: Immunohistochemistry was used to measure Shh, Gli1, FAK, p-FAK, and p-AKT expressions in 50 cases of HCC and paracancerous tissues. The Shh, Gli1, and FAK mRNA levels were determine...

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Bibliografiske detaljer
Udgivet i:Int J Clin Exp Pathol
Main Authors: Chen, Bin, Hu, Zeming, Li, Bofei, Lin, Xuan, Luo, Zhijiang, Hu, Zhiqiang
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2019
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949613/
https://ncbi.nlm.nih.gov/pubmed/31934065
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