Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway

It has been reported that there are multiple mechanisms by which bufalin could exert its antimetastatic effect. HIF-1α has been reported to be involved in tumor migration and invasion by regulating EMT. However, it is not known whether bufalin could exert the antimetastatic effect by modulating HIF-...

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Опубликовано в: :Oncotarget
Главные авторы: Wang, Haiyong, Zhang, Chenyue, Xu, Litao, Zang, Kun, Ning, Zhouyu, Jiang, Feng, Chi, Huiying, Zhu, Xiaoyan, Meng, Zhiqiang
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991447/
https://ncbi.nlm.nih.gov/pubmed/26958938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7935
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