SOCS5 inhibition induces autophagy to impair metastasis in hepatocellular carcinoma cells via the PI3K/Akt/mTOR pathway

SOCS5 is a member of the suppressor of cytokine signaling (SOCS) protein family with important yet incompletely understood biological functions in cancer. In hepatocellular carcinoma (HCC), controversial tumor-promoting and tumor-suppressive roles of SOCS5 have been reported. Our study aims to unrav...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Zhang, Mao, Liu, Shihai, Chua, Mei-Sze, Li, Haoran, Luo, Dingan, Wang, Sheng, Zhang, Shun, Han, Bing, Sun, Chuandong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690952/
https://ncbi.nlm.nih.gov/pubmed/31406106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1856-y
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