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Tumor sialylation impedes T cell mediated anti-tumor responses while promoting tumor associated-regulatory T cells
The increased presence of sialylated glycans on the tumor surface has been linked to poor prognosis, yet the effects on tumor-specific T cell immunity are hardly studied. We here show that hypersialylation of B16 melanoma substantially influences tumor growth by preventing the formation of effector...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891003/ https://ncbi.nlm.nih.gov/pubmed/26741508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6822 |
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