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Theoretical Insights into the Biophysics of Protein Bi-stability and Evolutionary Switches

Deciphering the effects of nonsynonymous mutations on protein structure is central to many areas of biomedical research and is of fundamental importance to the study of molecular evolution. Much of the investigation of protein evolution has focused on mutations that leave a protein’s folded structur...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Sikosek, Tobias, Krobath, Heinrich, Chan, Hue Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890782/
https://ncbi.nlm.nih.gov/pubmed/27253392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004960
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