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Single Molecule Cluster Analysis Identifies Signature Dynamic Conformations along the Splicing Pathway
The spliceosome is the dynamic RNA-protein machine responsible for faithfully splicing introns from precursor messenger RNAs (pre-mRNAs). Many of the dynamic processes required for the proper assembly, catalytic activation, and disassembly of the spliceosome as it acts on its pre-mRNA substrate rema...
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| Publicado no: | Nat Methods |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4890712/ https://ncbi.nlm.nih.gov/pubmed/26414013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3602 |
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