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Electrophoretic Deformation of Individual Transfer RNA Molecules Reveals Their Identity

It has been hypothesized that the ribosome gains additional fidelity during protein translation by probing structural differences in tRNA species. We measure the translocation kinetics of different tRNA species through ~3 nm diameter synthetic nanopores. Each tRNA species varies in the time scale wi...

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Détails bibliographiques
Publié dans:Nano Lett
Auteurs principaux: Henley, Robert Y., Ashcroft, Brian Alan, Farrell, Ian, Cooperman, Barry S., Lindsay, Stuart M., Wanunu, Meni
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890568/
https://ncbi.nlm.nih.gov/pubmed/26609994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.5b03331
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