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Electrophoretic Deformation of Individual Transfer RNA Molecules Reveals Their Identity

It has been hypothesized that the ribosome gains additional fidelity during protein translation by probing structural differences in tRNA species. We measure the translocation kinetics of different tRNA species through ~3 nm diameter synthetic nanopores. Each tRNA species varies in the time scale wi...

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Detalhes bibliográficos
Publicado no:Nano Lett
Main Authors: Henley, Robert Y., Ashcroft, Brian Alan, Farrell, Ian, Cooperman, Barry S., Lindsay, Stuart M., Wanunu, Meni
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890568/
https://ncbi.nlm.nih.gov/pubmed/26609994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.5b03331
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