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Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish

Upstream open reading frames (uORFs) are ubiquitous repressive genetic elements in vertebrate mRNAs. While much is known about the regulation of individual genes by their uORFs, the range of uORF-mediated translational repression in vertebrate genomes is largely unexplored. Moreover, it is unclear w...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chew, Guo-Liang, Pauli, Andrea, Schier, Alexander F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890304/
https://ncbi.nlm.nih.gov/pubmed/27216465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11663
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