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Induction of memory cytotoxic T cells to influenza A virus and subsequent viral clearance is not modulated by PB1-F2-dependent inflammasome activation

Expression of the viral virulence protein PB1-F2 during infection has been linked to NLRP3 inflammasome complex activation in macrophages and induction of early inflammatory events enhancing immunopathology during influenza disease. We sought to determine whether PB1-F2-specific NLRP3 inflammasome a...

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Библиографические подробности
Опубликовано в: :Immunol Cell Biol
Главные авторы: Lee, Patricia (Hoi Yee), Bird, Nicola, MacKenzie-Kludas, Charley, Mansell, Ashley, Kedzierska, Katherine, Brown, Lorena, McAuley, Julie
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890051/
https://ncbi.nlm.nih.gov/pubmed/26667784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2015.115
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