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TLR9-ERK-mTOR signaling is critical for autophagic cell death induced by CpG oligodeoxynucleotide 107 combined with irradiation in glioma cells

Synthetic oligodeoxynucleotides containing unmethylated CpG dinucleotides (CpG ODN) function as potential radiosensitizers for glioma treatment, although the underlying mechanism is unclear. It was observed that CpG ODN107, when combined with irradiation, did not induce apoptosis. Herein, the effect...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Li, Xiaoli, Cen, Yanyan, Cai, Yongqing, Liu, Tao, Liu, Huan, Cao, Guanqun, Liu, Dan, Li, Bin, Peng, Wei, Zou, Jintao, Pang, Xueli, Zheng, Jiang, Zhou, Hong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890034/
https://ncbi.nlm.nih.gov/pubmed/27251306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27104
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