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Development of CpG-Oligodeoxynucleotides for Effective Activation of Rabbit TLR9 Mediated Immune Responses

CpG-oligodeoxynucleotides (CpG-ODN) are potent immune stimuli being developed for use as adjuvants in different species. Toll-like receptor 9 (TLR9) is the cellular receptor for CpG-ODN in mammalian cells. The CpG-ODN with 18–24 deoxynucleotides that are in current use for human and mouse cells, how...

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Detalhes bibliográficos
Main Authors: Chuang, Tsung-Hsien, Lai, Chao-Yang, Tseng, Ping-Hui, Yuan, Chiun-Jye, Hsu, Li-Chung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182578/
https://ncbi.nlm.nih.gov/pubmed/25269083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108808
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