C-terminal region of bacterial Ku controls DNA bridging, DNA threading and recruitment of DNA ligase D for double strand breaks repair

Non-homologous end joining is a ligation process repairing DNA double strand breaks in eukaryotes and many prokaryotes. The ring structured eukaryotic Ku binds DNA ends and recruits other factors which can access DNA ends through the threading of Ku inward the DNA, making this protein a key ingredie...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: McGovern, Stephen, Baconnais, Sonia, Roblin, Pierre, Nicolas, Pierre, Drevet, Pascal, Simonson, Héloïse, Piétrement, Olivier, Charbonnier, Jean-Baptiste, Le Cam, Eric, Noirot, Philippe, Lecointe, François
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Genome Integrity, Repair and Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889933/
https://ncbi.nlm.nih.gov/pubmed/26961308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw149
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