C-terminal region of bacterial Ku controls DNA bridging, DNA threading and recruitment of DNA ligase D for double strand breaks repair

Non-homologous end joining is a ligation process repairing DNA double strand breaks in eukaryotes and many prokaryotes. The ring structured eukaryotic Ku binds DNA ends and recruits other factors which can access DNA ends through the threading of Ku inward the DNA, making this protein a key ingredie...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: McGovern, Stephen, Baconnais, Sonia, Roblin, Pierre, Nicolas, Pierre, Drevet, Pascal, Simonson, Héloïse, Piétrement, Olivier, Charbonnier, Jean-Baptiste, Le Cam, Eric, Noirot, Philippe, Lecointe, François
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889933/
https://ncbi.nlm.nih.gov/pubmed/26961308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw149
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