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Diverged composition and regulation of the Trypanosoma brucei origin recognition complex that mediates DNA replication initiation
Initiation of DNA replication depends upon recognition of genomic sites, termed origins, by AAA+ ATPases. In prokaryotes a single factor binds each origin, whereas in eukaryotes this role is played by a six-protein origin recognition complex (ORC). Why eukaryotes evolved a multisubunit initiator, an...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889932/ https://ncbi.nlm.nih.gov/pubmed/26951375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw147 |
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