Identification of ORC1/CDC6-Interacting Factors in Trypanosoma brucei Reveals Critical Features of Origin Recognition Complex Architecture

DNA Replication initiates by formation of a pre-replication complex on sequences termed origins. In eukaryotes, the pre-replication complex is composed of the Origin Recognition Complex (ORC), Cdc6 and the MCM replicative helicase in conjunction with Cdt1. Eukaryotic ORC is considered to be composed...

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Detalhes bibliográficos
Main Authors: Tiengwe, Calvin, Marcello, Lucio, Farr, Helen, Gadelha, Catarina, Burchmore, Richard, Barry, J. David, Bell, Stephen D., McCulloch, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297607/
https://ncbi.nlm.nih.gov/pubmed/22412905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032674
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