PrimPol prevents APOBEC/AID family mediated DNA mutagenesis

PrimPol is a DNA damage tolerant polymerase displaying both translesion synthesis (TLS) and (re)-priming properties. This led us to study the consequences of a PrimPol deficiency in tolerating mutagenic lesions induced by members of the APOBEC/AID family of cytosine deaminases. Interestingly, during...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Pilzecker, Bas, Buoninfante, Olimpia Alessandra, Pritchard, Colin, Blomberg, Olga S., Huijbers, Ivo J., van den Berk, Paul C.M., Jacobs, Heinz
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889928/
https://ncbi.nlm.nih.gov/pubmed/26926109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw123
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars