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RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth
In B cells infected by the cancer-associated Epstein-Barr virus (EBV), RUNX3 and RUNX1 transcription is manipulated to control cell growth. The EBV-encoded EBNA2 transcription factor (TF) activates RUNX3 transcription leading to RUNX3-mediated repression of the RUNX1 promoter and the relief of RUNX1...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889917/ https://ncbi.nlm.nih.gov/pubmed/26883634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw085 |
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