Modulation of Enhancer Looping and Differential Gene Targeting by Epstein-Barr Virus Transcription Factors Directs Cellular Reprogramming

Epstein-Barr virus (EBV) epigenetically reprogrammes B-lymphocytes to drive immortalization and facilitate viral persistence. Host-cell transcription is perturbed principally through the actions of EBV EBNA 2, 3A, 3B and 3C, with cellular genes deregulated by specific combinations of these EBNAs thr...

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Detalhes bibliográficos
Main Authors: McClellan, Michael J., Wood, C. David, Ojeniyi, Opeoluwa, Cooper, Tim J., Kanhere, Aditi, Arvey, Aaron, Webb, Helen M., Palermo, Richard D., Harth-Hertle, Marie L., Kempkes, Bettina, Jenner, Richard G., West, Michelle J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771879/
https://ncbi.nlm.nih.gov/pubmed/24068937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003636
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