RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth

In B cells infected by the cancer-associated Epstein-Barr virus (EBV), RUNX3 and RUNX1 transcription is manipulated to control cell growth. The EBV-encoded EBNA2 transcription factor (TF) activates RUNX3 transcription leading to RUNX3-mediated repression of the RUNX1 promoter and the relief of RUNX1...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Gunnell, Andrea, Webb, Helen M., Wood, C. David, McClellan, Michael J., Wichaidit, Billy, Kempkes, Bettina, Jenner, Richard G., Osborne, Cameron, Farrell, Paul J., West, Michelle J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Gene regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889917/
https://ncbi.nlm.nih.gov/pubmed/26883634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw085
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