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Hepcidin Plays a Key Role in 6-OHDA Induced Iron Overload and Apoptotic Cell Death in a Cell Culture Model of Parkinson's Disease

Background. Elevated brain iron levels have been implicated in the pathogenesis of Parkinson's disease (PD). However, the precise mechanism underlying abnormal iron accumulation in PD is not clear. Hepcidin, a hormone primarily produced by hepatocytes, acts as a key regulator in both systemic a...

詳細記述

保存先:
書誌詳細
出版年:Parkinsons Dis
主要な著者: Xu, Qi, Kanthasamy, Anumantha G., Jin, Huajun, Reddy, Manju B.
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889865/
https://ncbi.nlm.nih.gov/pubmed/27298749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8684130
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