Aromatase Expression in the Hippocampus of AD Patients and 5xFAD Mice

Numerous studies show that 17β-estradiol (E(2)) protects against Alzheimer's disease (AD) induced neurodegeneration. The E(2)-synthesizing enzyme aromatase is expressed in healthy hippocampi, but although the hippocampus is severely affected in AD, little is known about the expression of hippoc...

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Détails bibliographiques
Publié dans:Neural Plast
Auteurs principaux: Prange-Kiel, Janine, Dudzinski, Danuta A., Pröls, Felicitas, Glatzel, Markus, Matschke, Jakob, Rune, Gabriele M.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889864/
https://ncbi.nlm.nih.gov/pubmed/27298742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9802086
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