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Chemogenetic Modulation of Astrocytic Activity Rescues Hippocampus Associated Neurodegeneration in Alzheimer’s Disease Mice Model 5xFAD

Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder characterized by Aβ-amyloid accumulation and cognitive decline. Despite extensive research, effective treatments remain elusive. Astrocytes, the most abundant glial cells, play a crucial role in synaptic transmission, neuronal excita...

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Bibliografiske detaljer
Main Authors: Evgenii Gerasimov, Maria Berg, Anastasia Bolshakova, Ilya Bezprozvanny, Olga Vlasova
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-01-01
Serier:Neural Plasticity
Online adgang:http://dx.doi.org/10.1155/np/9880933
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