Targeting the PI3K/Akt pathway in murine MDS/MPN driven by hyperactive Ras

Chronic and juvenile myelomonocytic leukemias (CMML and JMML) are myelodysplastic/myeloproliferative neoplasia (MDS/MPN) overlap syndromes that respond poorly to conventional treatments. Aberrant Ras activation due to NRAS, KRAS, PTPN11, CBL, and NF1 mutations is common in CMML and JMML. However, no...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Leukemia
Main Authors: Akutagawa, Jon, Huang, Tannie Q., Epstein, Inbal, Chang, Tiffany, Quirindongo-Crespo, Maricel, Cottonham, Charisa L., Dail, Monique, Slusher, Barbara S., Friedman, Lori S., Sampath, Deepak, Braun, Benjamin S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889473/
https://ncbi.nlm.nih.gov/pubmed/26965285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.14
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla