IGF2BP3 modulates the interaction of invasion-associated transcripts with RISC

Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) expression correlates with malignancy. But its role(s) in pathogenesis remain enigmatic. Here, we interrogated the IGF2BP3-RNA interaction network in pancreatic ductal adenocarcinoma (PDAC) cells. Using a combination of genome-wide approa...

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Publicado en:Cell Rep
Autores principales: Ennajdaoui, Hanane, Howard, Jonathan M., Sterne-Weiler, Timothy, Jahanbani, Fereshteh, Coyne, Doyle J., Uren, Philip J., Dargyte, Marija, Katzman, Sol, Draper, Jolene M., Wallace, Andrew, Cazarez, Oscar, Burns, Suzanne C., Qiao, Mei, Hinck, Lindsay, Smith, Andrew D., Toloue, Masoud M., Blencowe, Benjamin J., Penalva, Luiz O.F., Sanford, Jeremy R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889463/
https://ncbi.nlm.nih.gov/pubmed/27210763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.083
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