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IGF2BP3 modulates the interaction of invasion-associated transcripts with RISC

Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) expression correlates with malignancy. But its role(s) in pathogenesis remain enigmatic. Here, we interrogated the IGF2BP3-RNA interaction network in pancreatic ductal adenocarcinoma (PDAC) cells. Using a combination of genome-wide approa...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ennajdaoui, Hanane, Howard, Jonathan M., Sterne-Weiler, Timothy, Jahanbani, Fereshteh, Coyne, Doyle J., Uren, Philip J., Dargyte, Marija, Katzman, Sol, Draper, Jolene M., Wallace, Andrew, Cazarez, Oscar, Burns, Suzanne C., Qiao, Mei, Hinck, Lindsay, Smith, Andrew D., Toloue, Masoud M., Blencowe, Benjamin J., Penalva, Luiz O.F., Sanford, Jeremy R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889463/
https://ncbi.nlm.nih.gov/pubmed/27210763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.083
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