IGF2BP3 modulates the interaction of invasion-associated transcripts with RISC

Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) expression correlates with malignancy. But its role(s) in pathogenesis remain enigmatic. Here, we interrogated the IGF2BP3-RNA interaction network in pancreatic ductal adenocarcinoma (PDAC) cells. Using a combination of genome-wide approa...

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Vydáno v:Cell Rep
Hlavní autoři: Ennajdaoui, Hanane, Howard, Jonathan M., Sterne-Weiler, Timothy, Jahanbani, Fereshteh, Coyne, Doyle J., Uren, Philip J., Dargyte, Marija, Katzman, Sol, Draper, Jolene M., Wallace, Andrew, Cazarez, Oscar, Burns, Suzanne C., Qiao, Mei, Hinck, Lindsay, Smith, Andrew D., Toloue, Masoud M., Blencowe, Benjamin J., Penalva, Luiz O.F., Sanford, Jeremy R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889463/
https://ncbi.nlm.nih.gov/pubmed/27210763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.083
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