Selective sorting and destruction of mitochondrial membrane proteins in aged yeast

Mitochondrial dysfunction is a hallmark of aging, and underlies the development of many diseases. Cells maintain mitochondrial homeostasis through a number of pathways that remodel the mitochondrial proteome or alter mitochondrial content during times of stress or metabolic adaptation. Here, using y...

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Bibliographic Details
Published in:eLife
Main Authors: Hughes, Adam L, Hughes, Casey E, Henderson, Kiersten A, Yazvenko, Nina, Gottschling, Daniel E
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2016
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889329/
https://ncbi.nlm.nih.gov/pubmed/27097106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13943
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