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The non-canonical functions of p27(Kip1) in normal and tumor biology

p27(Kip1) was first discovered as a key regulator of cell proliferation. The canonical function of p27(Kip1) is inhibition of cyclin-dependent kinase (CDK) activity. In addition to its initial identification as a CDK inhibitor, p27(Kip1) has also emerged as an intrinsically unstructured, multifuncti...

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Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Sharma, Savitha S., Pledger, W. Jackson
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889241/
https://ncbi.nlm.nih.gov/pubmed/27082696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1157238
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