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p27Kip1 inhibits the cell cycle through non-canonical G1/S phase-specific gatekeeper mechanism

The cyclin-dependent kinase (CDK) inhibitor p27Kip1 has been shown to regulate cellular proliferation via inhibition of CDK activities. It is now recognized that p27Kip1 can regulate cellular processes through non-canonical, CDK-independent mechanisms. We have developed an inducible p27Kip1 model in...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Sharma, Savitha S, Ma, Le, Pledger, W Jackson
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825794/
https://ncbi.nlm.nih.gov/pubmed/26697844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1100775
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