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Severe mitochondrial damage associated with low-dose radiation sensitivity in ATM- and NBS1-deficient cells

Low-dose radiation risks remain unclear owing to a lack of sufficient studies. We previously reported that low-dose, long-term fractionated radiation (FR) with 0.01 or 0.05 Gy/fraction for 31 d inflicts oxidative stress in human fibroblasts due to excess levels of mitochondrial reactive oxygen speci...

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Библиографические подробности
Опубликовано в: :Cell Cycle
Главные авторы: Shimura, Tsutomu, Kobayashi, Junya, Komatsu, Kenshi, Kunugita, Naoki
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889229/
https://ncbi.nlm.nih.gov/pubmed/26940879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1156276
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