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Comparison of human coagulation factor VIII expression directed by cytomegalovirus and mammary gland-specific promoters in HC11 cells and transgenic mice

Hemophilia A is an inherited X-linked recessive bleeding disorder caused by coagulant factor VIII (FVIII) deficiency. The conventional treatment involves the administration of recombinant human FVIII (rhFVIII) preparations. In this study, the mammary gland ‘bioreactor’ is designed to specifically an...

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Vydáno v:Blood Coagul Fibrinolysis
Hlavní autoři: Wang, Qing, Hao, Siguo, Ma, Liyuan, Zhang, Wenhao, Wan, Jiangbo, Deng, Xiaohui
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams And Wilkins 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888922/
https://ncbi.nlm.nih.gov/pubmed/26192111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MBC.0000000000000318
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