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Comparison of human coagulation factor VIII expression directed by cytomegalovirus and mammary gland-specific promoters in HC11 cells and transgenic mice

Hemophilia A is an inherited X-linked recessive bleeding disorder caused by coagulant factor VIII (FVIII) deficiency. The conventional treatment involves the administration of recombinant human FVIII (rhFVIII) preparations. In this study, the mammary gland ‘bioreactor’ is designed to specifically an...

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Detalhes bibliográficos
Publicado no:Blood Coagul Fibrinolysis
Main Authors: Wang, Qing, Hao, Siguo, Ma, Liyuan, Zhang, Wenhao, Wan, Jiangbo, Deng, Xiaohui
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams And Wilkins 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888922/
https://ncbi.nlm.nih.gov/pubmed/26192111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MBC.0000000000000318
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